Diffusion weighted imaging dwi is a form of mr imaging based upon measuring the random brownian motion of water molecules within a voxel of tissue in general simplified terms highly cellular tissues or those with cellular swelling exhibit lower diffusion coefficients. Diffusion mri is an active area of research that produces an unprecedented wealth of information on white matter anatomy future refinement of diffusion mri tools for mapping white matter pathways will continue to advance tissue characterization surgical planning and follow up of brain tumor patients. Diffusion mri dmri is widely used by clinicians and radiologists to diagnose neurological disorders in particular stroke the most commonly encountered diffusion technique in the clinic is . Diffusion refers to the random microscopic movement of water and other small molecules due to thermal collisionsdiffusion is also known as brownian motion named in honor of scottish botanist robert brown who first observed spontaneous vibration of pollen particles under the microscope in 1827
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